It was an important landing place at the time of the Romans (or even at the time of the Greeks for the export of excellent wine) active until the beginning of the 17th century, but which was abandoned after the reconstruction of the port of Pesaro (1614).
You could easily enter Vallugola through the Via Flaminia.
It seems that the toponym means "Valley of the little wines": it is possible, since the wine, together with flour, wheat, favas, and figs, was on of the traded products.
Further info (Italian text)
Province: Pesaro and Urbino Region: the Marches